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ea0081oc9.1 | Oral Communications 9: Environmental Endocrinology | ECE2022

Higher free thyroxine associated with pfas exposure in first trimester. The odense child cohort

Jensen Richard Christian , Glintborg Dorte , Timmermann Clara Amalie Gade , Nielsen Flemming , Boye Henriette , Bilenberg Niels , Madsen Jeppe Buur , Grandjean Philippe , Jensen Tina Kold , Andersen Marianne

Background: Perfluoroalkyl substances (PFAS) are endocrine disrupting chemicals, with elimination half-lives ranging from four to eight years. Experimental studies found PFAS able to interfere with thyroid hormone-binding proteins. During the first 20 weeks of gestation (GW), the fetus is reliant on placental transfer of maternal thyroid hormones, mainly free thyroxine (FT4). However, previous studies investigating associations between exposure to PFAS and thyroid hormone stat...

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ea0092op-04-04 | Oral Session 4: Young Investigators / Clinical and Translational | ETA2023

The association between maternal thyroid function and language acquisition in offspring aged 12 to 37 months: an odense child cohort study

Ryom Riis Kamilla , Joop Bonnema Steen , Fenger Dreyer Anja , Kold Jensen Tina , Glintborg Dorte , Bilenberg Niels , Bleses Dorthe , Trecca Fabio , Andersen Marianne

Introduction: Maternal thyroid function in early pregnancy is crucial for fetal neural development. Early offspring language acquisition is an important indicator of fetal neural development and a predictor of future cognitive development. We aimed to investigate how the mothers thyroid function and the presence of thyroid autoimmunity in early pregnancy are associated with offsprings language acquisition at the age of 12-37 months.Methods: T...

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Endocrine Abstracts

Higher free thyroxine associated with pfas exposure in first trimester. The odense child cohort

The association between maternal thyroid function and language acquisition in offspring aged 12 to 37 months: an odense child cohort study

BiosciAbstracts